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KMID : 0358319820230020210
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Korean Journal of Urology
1982 Volume.23 No. 2 p.210 ~ p.215
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Urinary Prostaglandin E in Female Urethral Syndrome
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최한용/Choi HY
주근원/Choo KW
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Abstract
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The levels of prostaglandin E were studied in the urine of 25 female patients with irritative bladder symptoms but no evidence of organic disease or urinary infection (female urethral syndrome). Twenty five healthy women served as a control group. A significant elevation of prostaglandin E in the urine of patient with female urethral syndrome was demonstrated (by Wilcoxon rank sum test; z= -2.32, p<0.05).
The results suggest that prostaglandins may be responsible for the lower urinary tract symptoms in the patients. The potential beneficial clinical effects of prostaglandin syntheses inhibitors in treatingthe severe discomfort associated with urethral syndrome need to be evaluated further.
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